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Microsoft

Microsoft 365 and Defender delivery

Separate sender-side failures from recipient tenant filtering and mail-flow policy.

Identify the receiving system

A corporate domain can use Microsoft 365 with additional gateways and tenant-specific policies. Outlook.com SNDS data does not explain every Microsoft 365 decision. Collect the complete non-delivery report or the headers of an accepted message and identify which hop made the decision.

Read the available evidence

EvidenceUse
Complete NDRRead the diagnostic text, generating server and remote response. 550 5.7.1 alone is not a unique diagnosis.
Authentication-ResultsCheck the authentication outcomes and evaluated identities at the trusted receiver.
X-Forefront-Antispam-ReportConsult Microsoft’s documented fields, including CAT and DIR, to understand filtering context.
Recipient-side trace or quarantineAsk the authorized tenant administrator to identify the actual action and matching policy.

Interpret the documented fields together with the recipient-side trace. Internal values and individual header numbers do not provide a complete explanation of cloud filtering.

Resolve the actual cause

  1. Repair sender authentication or message-generation faults identified by the evidence.
  2. For a recipient restriction or mail-flow rule, ask the recipient administrator to review the intended policy.
  3. For suspected false detection, preserve the original message and ask the authorized administrator to use Microsoft’s submission workflow.
  4. Retest with a newly generated message through the same route, then compare the recipient-side result.

Sources